Topic: electrical synapses

I am working on the vertebrate retina, with a main focus on the mouse and bird retina. Currently my work is focused on three major topics: Functional and molecular analysis of electrical synapses in the retina Circuitry and functional role of retinal interneurons: horizontal cells Circuitry for light-dependent magnetoreception in the bird retina Electrical synapses Electrical synapses (gap junctions) permit fast transmission of electrical signals and passage of metabolites by means of channels, which directly connect the cytoplasm of adjoining cells. A functional gap junction channel consists

The medial Prefrontal Cortex (mPFC) receives and coordinates signals from many brain regions and is an executive hub for the interplay of sensory, limbic, and motor information. Layer 1 (L1) interneurons are essential for signal integration within the mPFC, and they are known to play a role in the maintenance of brain oscillations. However, little is known about the plasticity of electrical synapses (ES) in the L1 of the mPFC. By paired patch-clamp recordings on acute brain slices, we provide novel and conclusive evidence of functional ES between interneurons in L1 of the mPFC. ES in L1 of mPF