Topic: FinnBrain Birth Cohort Study

Emerging evidence suggests that intrauterine exposures to maternal factors such as to maternal pre-pregnancy body mass index (MBMI) impacts the neurodevelopment of the offspring in a region-specific way, possibly contributing to future obesity risk of the offspring. Our study investigates the associations between MBMI and neonatal global white matter integrity in 157 infant-mother dyads from FinnBrain Birth Cohort Study (www.finnbrain.fi). Following TBSS (Tract-based Spatial Statistics) skeletonization, associations between MBMI and mean diffusivity values were assessed using a voxel-wise non-

Maternal pre- and postnatal depressive symptoms influence brain development in offspring through intrauterine conditions as well as ways of parenting and mother–child interaction. This study investigated whether maternal perinatal depressive symptoms associate with child’s whole brain regional homogeneity (ReHo) and seed-based connectivity of the bilateral amygdala at 5 years of age based on the sample available from FinnBrain Birth Cohort Study (N = 68; 40 female). Maternal depressive symptoms were assessed with the Edinburgh Postnatal Depression Scale (EPDS) at gestational week 24, 3, 6, and