Topic: functional magnetic resonance imaging

The understanding of the stroke lesions’ consequences is limited, and it relies mostly on behavioral reports and mere descriptive correlational information from neuroimaging techniques. Using functional magnetic resonance imaging, it has been shown that the functional synchronization between distinct regions of the brain, referred to as functional connectivity, is disrupted by stroke. Nevertheless, this kind of data is usually large and high-dimensional. Extracting useful information from the vast amount of information afforded by brain networks remains a great challenge so, in order to make s

Grid cells are neurons in the entorhinal cortex that are thought to perform computations in support of spatial navigation. As direct recordings of grid cells from the human brain are only rarely possible, functional magnetic resonance imaging (fMRI) studies proposed and described an indirect measure of entorhinal grid-cell activity, which is quantified as a hexadirectional modulation (HM) of fMRI activity as a function of the subject’s movement direction through a virtual environment. However, the contributing role of the aggregated activity of grid cells to this modulation remains unclear. Ou

Mounting evidence suggests that autobiographical memory is crucially dependent on our ability to construct visual mental images. Indeed, we have found previously that aphantasics (people who cannot construct mental images) have more difficulties to recall personal memories than controls and that aphantasics showed decreased hippocampal activation during autobiographical memory. While aphantasia is a subjective condition of deficient mental imagery, in a follow-up study, we examine the neural correlates of autobiographical memory in a very rare patient population, people who are blind from birt

The correlation between cognitive function, mood states, and driving behavior remains unclear. Hence, we aimed to explore this relationship objectively, by functional magnetic resonance imaging (fMRI). In a cross-sectional design, 28 male 20 to 30-year-old drivers were randomly included in the study. Each participant drove virtually in an fMRI-compatible driving simulator, after auditory and visual induction of positive, negative, and neutral mood; and fMRI was performed meanwhile to explore brain activity alterations. The analysis was performed using SPM software by performing seed-based conn