Topic: magnetic resonance imaging

The human brain is a heavily interconnected structure giving rise to complex functions. While brain functionality is mostly revealed during wakefulness, the sleeping brain might offer another view into physiological and pathological brain connectivity. Furthermore, there is a large body of evidence supporting that sleep mediates plastic changes in brain connectivity. Although brain plasticity depends on environmental input which is provided in the waking state, disconnection during sleep might be necessary for integrating new into existing information and at the same time restoring brain effic

Cross-sectional and longitudinal multimodal brain imaging studies using positron emission tomography (PET) and magnetic resonance imaging (MRI) have provided detailed insight into the pathophysiological progression of Alzheimer’s disease. It starts at an asymptomatic stage with widespread gradual accumulation of beta-amyloid and spread of pathological tau deposits. Subsequently changes of functional connectivity and glucose metabolism associated with mild cognitive impairment and brain atrophy may develop. However, the rate of progression to a symptomatic stage and ultimately dementia varies c

There is currently a paucity of neuroimaging data from the African continent, limiting the diversity of data from a significant proportion of the global population. This in turn diminishes global health research and innovation. To address this issue, we present and describe the first Magnetic Resonance Imaging (MRI) dataset from individuals in the African nation of Nigeria. This dataset contains pseudonymized structural MRI (T1w, T2w, FLAIR) data of clinical quality, with 33 images from healthy control subjects, 32 images from individuals diagnosed with age-related dementia and 21 from individ