This conference examines the origins, distribution and consequences of mutations across cells, tissues, organisms and populations. Improved sequencing accuracy, experimental perturbations, multi-omic measurements and computational analysis are brought together to study genetic heterogeneity and its effects on genome function, evolution and disease. Sessions address mechanisms of mutagenesis, technologies for detecting and interpreting mutations, variation across the tree of life, tissue-level diversity, and evolutionary dynamics in cancer and other diseases. Researchers from genomics, mutagene
In Biology and Cancer Biology