Parallel Squared Technology Institute is recruiting scientist and senior-scientist candidates to use single-cell proteomics to investigate protein dysfunction in Alzheimer's disease and related neurodegenerative conditions. The work spans human brain tissue, molecular mechanisms, single-cell analysis, and computational biology in an interdisciplinary team.
In Biology and Molecular Biology
Seminar · Neuroimmunology
Neuroinflammation in Epilepsy: what have we learned from human brain tissue specimens ?
Eleonora Aronica · Amsterdam UMC
Wed, Oct 25, 2023 · 18:00 UTC
Epileptogenesis is a gradual and dynamic process leading to difficult-to-treat seizures. Several cellular, molecular, and pathophysiologic mechanisms, including the activation of inflammatory processes. The use of human brain tissue represents a crucial strategy to advance our understanding of the underlying neuropathology and the molecular and cellular basis of epilepsy and related cognitive and behavioral comorbidities, The mounting evidence obtained during the past decade has emphasized the critical role of inflammation in the pathophysiological processes implicated in a large spectrum o