Brain tissue

…transcriptomic analysis of brain tissue in the School of Psychology. The researcher will collect, process and interpret gene-expression data, maintain reproducible open-source analysis workflows, and contribute to data governance, publications and student supervision. This is a two-year, full-time Level A appointment of 35 hours per week in Sydney. Salary: AUD 118,000–126,000 plus 17% superannuation and annual leave loading. The application deadline is 9 November 2026.

Available treatments for brain disorders are commonly pharmacological in nature. Yet, the efficacy and the risk/benefit ratio of brain therapeutics -when they exist- are often dampened by the selectivity of the blood-brain barrier and off-target actions of the molecules, at the periphery as well as in the brain. To improve the efficacy of therapeutic molecules for the brain, their loading in polymersomes (synthetic polymer vesicles) represents a promising strategy due to their high stability, versatility and ability to transport drugs with high efficiency. However, encapsulation does not allow

…through microscopic and macroscopic brain structures. Energy flow through brain circuits is powered by thousands of mitochondria populating the inside of every neuron, glial, and other nucleated cell across the brain-body unit. This seminar will cover emerging approaches to study the mind-mitochondria connection and present early attempts to map the distribution and diversity of mitochondria across brain tissue. In rodents, I will present convergent multimodal evidence anchored in enzyme activities, gene expr