Scientist I/II, Expansion Microscopy

Develop and scale the expansion microscopy that prepares brain tissue for E11 Bio’s light-microscopy connectomics. The scientist runs bench experiments in the sample-production pipeline, improves gel performance and signal retention across repeated rounds of immunostaining, imaging and signal removal, defines quantitative quality metrics for gels and images, and works towards whole-brain gelation and expansion.

PhD in biology, chemistry, bioengineering, materials science, mechanical engineering or a related field, or equivalent experience; a record of owning experiments end to end and developing protocols, ideally in hydrogel chemistry, expansion microscopy, immunohistochemistry or tissue processing. Light-sheet or spinning-disc microscopy, quantitative scoring of imaging data and lab automation are preferred. Salary $100,000–170,000.