Topic: hypoxia

Burst-suppression (BS) is a highly structured electroencephalogram (EEG) pattern characterized by alternating periods of high-voltage activity (bursts) and low or flatline activity (suppression). In non-anesthetized adults, BS indicates severe brain pathology, e.g. due to oxygen and glucose deprivation [1]. There are two types of BS: one with identical bursts that are highly periodic and uniform in shape, often signaling a poor prognosis, and one without identical bursts [2]. The neuronal mechanisms behind BS and these variations remain largely unknown. Some studies suggest the involvement of

Animals are dynamical systems possessing a wide range of capabilities mediated by interactions between their constitutive cells. The brain, central integrator and coordinator of bodily output, solves problems in the context of bodily needs, driven by external environmental signals and internal bodily signals. While neuroscience has progressed in the ability to measure neurons and environment at ever great scale and resolution, our ability to measure activity within the rest of the body and relate these to neuronal computation remains limited. Here, we extend the principles and tools of neurosc