Topic: intergenerational transmission

Background: The corticolimbic tract (CLT), encompassing subcortical and neocortical areas, is linked to socioemotional skills such as emotion processing and regulation. Alterations in CLT structure, function, and connectivity are associated with socioemotional deficits and are reported for different psychopathologies. An increased knowledge of the mechanisms supporting healthy CLT development, including biological and environmental factors, may further our understanding of socioemotional disorders in childhood and adolescence, ultimately impacting early identification and treatment. Here, we a

Maternal pre- and postnatal depressive symptoms influence brain development in offspring through intrauterine conditions as well as ways of parenting and mother–child interaction. This study investigated whether maternal perinatal depressive symptoms associate with child’s whole brain regional homogeneity (ReHo) and seed-based connectivity of the bilateral amygdala at 5 years of age based on the sample available from FinnBrain Birth Cohort Study (N = 68; 40 female). Maternal depressive symptoms were assessed with the Edinburgh Postnatal Depression Scale (EPDS) at gestational week 24, 3, 6, and