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Topic: light microscopy

ePoster
1 ePoster

In Biology and Computational Neuroscience

ePoster · Computational Neuroscience

Reconsideration of local spatial connectivity and target specificity in the cortical microcircuit based on volumetric reconstruction

Anno Kurth, Jasper Albers, Markus Diesmann, Sacha van Albada · Bernstein Conference 2024

Microcircuits are the fundamental building blocks of the neocortex [1]. Single instances have been reconstructed experimentally (e.g., [2]), and their general dynamics and information processing capabilities have been investigated theoretically (e.g., [3, 4, 5, 6, 7]). Their architecture is usually represented in connectivity maps consisting of probabilities that neurons establish connections. These maps reduce the complicated circuitry to simple relations between cell types, allowing for efficient instantiations of neural network models in parallel computers [8]. While this approach neglects