Topic: malondialdehyde

The effect of living conditions on the physiology, behaviour and stress of laboratory animals is still being discussed. There are conflicting findings regarding individually ventilated cages(IVC). This study aims to explore the effects of three distinct cage setups and to examine the differences in the impacts of IVC cages, classical cages and classical cages with varying mouse populations. Thirty male C57BL/6J strain mice were split into three groups:IVC, classical small(CC500) and big(CC800) with a floor size of 500 and 800 cm2,respectively. From birth until six months of age, the mice were

Almost all body functions undergo circadian variations synchronized by light/dark cycle-regulated melatonin secretion from the pineal gland. Circadian disruption reduces melatonin secretion and increases the risk of diabetes and its complications, including anxiety. We aimed to study the effects of reduced daily light exposure on diabetes-associated anxiety-like behavior and brain oxidative stress in streptozotocin-treated rats. Male Wistar rats were divided into the following groups: 1. control (C12/12), saline-treated group with light/dark cycle 12/12h; 2. saline-treated group on light/dark