Metabolism

…studying inflammation, angiogenesis, metabolism, genetic and epigenetic regulation, and tumour immunity. The scientific focus connects mechanisms of cancer initiation, progression and metastasis with the tumour microenvironment and their potential therapeutic implications. Applicants submit their research vision and supporting academic material

…spanning angiogenesis, inflammation, metabolism, genetic and epigenetic regulation, and cancer immunology. The research objective is to clarify mechanisms of tumour initiation, progression and metastatic dissemination and connect fundamental findings with therapeutic development. The employer provides a role-specific online applicat

…senescence, protein homeostasis, metabolism, mitochondrial biology, genome stability, epigenetic regulation, stem cells and the neurobiology of aging. The appointment includes teaching, mentoring, collaborative research and university service. Priority review is 15 November 2026.

…flexibility, condensates, metabolism, cell biology and human disease. Emerging technologies, computational analysis and AI-based modelling connect classical RNA-binding proteins with newly identified intera

…and policy, emphasizing nutrition, metabolism, food systems and translation of evidence into better health. Abstracts are due February 1, 2027, at noon Eastern, with a late-breaking round closing March 4. Presenters must register by March 24; late-breaking abstracts are excluded from abstract awards and APNM

A joint investigator and tenure-track assistant-professor opportunity for an independent metabolism research programme. Potential university homes include Chemical and Biological Engineering, Medical Microbiology and Immunology, and Neuroscience. The search welcomes work on metabolic engineering, host–microbe interactions, immunometabolism and brain metabolism. Applicants should submit a CV, research and teaching plans, and arrange three references using the email instructions on the official page. Full-consideration review is 1 November 2026; applications continue on a rolling basis thereafte

…Relevant areas include epigenetics, metabolism, stem cells, single-cell analysis, functional screening and gene delivery. Multiple scientist levels are available, with advertised salary bands spanning USD 116,450–247,000 depending on level.

Develop bioelectronic interfaces for monitoring metabolism and controlling cellular behaviour. Projects combine catalyst design, computational modelling, bioelectrode fabrication and electrical engineering, with opportunities to build implant concepts and control software.

This EMBO Workshop connects organelle contact sites and cytoskeletal interactions with metabolism, signalling, and trafficking, and examines their relevance to neurodegeneration, cancer, and other diseases.

Different brain cell types exhibit distinct metabolic signatures that link energy economy to cellular function. Astrocytes and neurons, for instance, diverge dramatically in their reliance on glycolysis versus oxidative phosphorylation, underscoring that metabolic fuel efficiency is not uniform across cell types. A key factor shaping this divergence is the structural organization of the mitochondrial respiratory chain into supercomplexes. Specifically, complexes I (CI) and III (CIII) form a CI–CIII supercomplex, but the degree of this assembly varies by cell type. In neurons, CI is predominant

…role in regulating appetite and metabolism. It has been shown that activity changes in these neurons are necessary and sufficient to acutely regulate feeding behavior. TH neurons send dense intrahypothalamic axonal projections and make synaptic connections to paraventricular nucleus (PVN), which have been shown to be the key downstream target region. Since the ARCTH→PVN synaptic connection plays a crucial role in feeding, possible changes in the strength of this connection are also likely t

…to immunosuppression and a changed metabolism. However, if the stress becomes chronic, the coping systems can be maladaptively altered. In addition, glucocorticoid levels follow a daily circadian rhythm with a peak in the morning just before the organism starts to become active. While it is known that chronic stress can lead to a disruption of the circadian rhythm, it is still not fully understood how the long-term effects after chronic stress and th

Metabolism actively interacts with the proteome, transcriptome, and genome, thereby influencing all facets of biological information and providing cells the adaptability required for optimal functioning across time and space. Neurodevelopment, in particular, depends on the timely integration of numerous molecular signals across cell types, thus deeply relying on metabolite signaling functions. Although measuring changes in metabolites is useful to describe the association between molecules and disorders, the molecular mechanisms through which these metabolites affect neurodevelopment remain un

…Metabolism-based therapies can restore PV-IN function after inju

Little is known about the critical metabolic changes that neural cells have to undergo during development and how temporary shifts in this program can influence brain circuitries and behavior. Motivated by the identification of autism-associated mutations in SLC7A5, a transporter for metabolically essential large neutral amino acids (LNAAs), we utilized metabolomic profiling to investigate the metabolic states of the cerebral cortex across various developmental stages. Our findings reveal significant metabolic restructuring occurring in the forebrain throughout development, with specific group

Gut-derived signals regulate metabolism, appetite, and behaviors important for mental health. We have performed a large-scale multidimensional screen to identify gut hormones and nutrient-sensing mechanisms in the intestine that regulate metabolism and behavior in the fruit fly Drosophila. We identified several gut hormones that affect fecundity, stress responses, metabolism, feeding, and sleep behaviors, many of which seem to act sex-specifically. We show that in response to nutrient intake, the enteroendocrine cells (EECs) of the adult Drosophila midgut release hormones that act via inter-or

…same time, bodily processes, such as metabolism can also impact economic behavior. These modulations can occur through our social networks, through the impact of

…with nicotinate and nicotinamide metabolism, which is critic

…These global patterns alter energy metabolism in the brain over seconds to hours, making oxygen consumption and glucose uptake widely used proxies of neural activity. However, whether changes in neural activity are causally related to changes in metabolic flux in intact circuits on the sub-second timescales associated with behavior, is unclear. Moreover, it is unclear whether differences between rest and action are associated

…and storage, to signaling and metabolism. While it is clear that these compartments represent a type of separated phase, what controls their formation, how specific biological components are included or excluded, and how these structures influence physiological and biochemical processes re

…is mostly provided by carbohydrate metabolism. Neurons are very sensitive to changes in the extracellular fluid surrounding them, which necessitated shielding of the nervous system from fluctuating solute concentrations in circulation. This is achieved by the blood-brain barrier (BBB) that prevents paracellular diffusion of solutes into the nervous system. This in turn also means that all nutrients that are needed e.g. for sufficient energy supply need to be transported over the BBB. We use Drosophila as a model sy