Topic: mixing

Lead lipid-nanoparticle formulation, characterisation and process scale-up for investigational gene-editing therapies. Responsibilities span mixing and tangential-flow filtration from bench to GLP/GMP scale, process optimisation, external manufacturing transfer and contributions to regulatory CMC documentation. The position connects delivery technology with manufacturable drug products and involves collaboration with research, platform and therapeutic teams. The advertised annual base salary is USD 145,000–161,000, with additional incentive eligibility.

A January–June 2027 process engineering placement developing targeted lipid nanoparticle formulations in Cambridge, Massachusetts. The work investigates mixing, filtration and tangential-flow filtration, and links process conditions to nanoparticle quality, stability and scalability. The student designs and executes experiments, analyses performance and works with analytical and process development colleagues on manufacturing challenges.