Topic: myo-inositol

Social status is key to mental health and well-being. The nucleus accumbens (NAc) regulates motivated behaviors, including the establishment of social hierarchies. Our recent work underscored NAc mitochondrial energy metabolism as critical for social competition among rodents. However, the exact neurochemical and molecular underpinnings of the differences in NAc energy metabolism and the specific contribution of distinct cell types are yet to be determined. Magnetic resonance spectroscopy (MRS) allows the study of metabolites related to energy metabolism, neurotransmission, and cellular integr

Epilepsy, a debilitating illness characterized by seizures, often proves resistant to medication necessitating surgical intervention. Advanced MRI techniques, notably 7T MRI, can offer improved lesion detection. However, patients without structural abnormalities pose a particular challenge. In such cases, 7T Magnetic Resonance Spectroscopy Imaging (MRSI) may prove beneficial in identifying subtle metabolic alterations though higher spectral resolution, allowing the separation of metabolites with overlapping resonance frequencies such as glutamate and glutamine, key metabolites in excitatory pr