Topic: nerve stimulation

The brain must differentiate between externally-generated and self-generated sensory inputs to build stable perception and generate appropriate behavior. Despite recent advances in neuroprostheses, little is known about how the brain interprets prosthetic sensory input, especially when self-generated. Here, we asked: How does the brain learn to distinguish self-generated prosthetic stimulation? To do this, we leveraged the well-understood neural pathways and behavior readouts of the vestibular system. A monkey was implanted with a vestibular prosthesis that restores sensory information via ner

Neural interfaces to peripheral nerves are increasingly employed for basic research, neuroprosthetics, and bioelectronic medicine (‘electroceuticals’). We previously established a pipeline for hybrid electromagnetic-electrophysiology modeling of nerve stimulation on the o2S2PARC platform for collaborative, FAIR, and reproducible computational neurosciences. It leverages histological data to generate a detailed anatomical model of the nerve microstructure and to functionalize it with populations of fiber neuro-dynamics models (myelinated/unmyelinated, statistical distributions of fiber types an