Neurobiological mechanisms

…nature and focus on understanding the neurobiological mechanisms underlying substance use disorders (SUD), including fundamental circuitry and behavior relevant to substance use. For projects not requiring a phased research approach, applicants are encouraged to apply under a different funding activity code (e.g., PA-25-305 "Research Project Grant (Parent R01 Clinical Trial Required)" or its subsequent reissue).

Human society operates on large-scale cooperation and shared norms of fairness. However, individual differences in cooperation and incentives to free-riding on others’ cooperation make large-scale cooperation fragile and can lead to reduced social-welfare. Deciphering the neural codes representing potential rewards/costs for self and others is crucial for understanding social decision-making and cooperation. I will first talk about how we integrate computational modeling with functional magnetic resonance imaging to investigate the neural representation of social value and the modulation by ox