Topic: neurodegenerative disorder

Huntington’s disease (HD) is a hereditary neurodegenerative disorder marked by progressive motor and cognitive decline caused by a mutation in the huntingtin gene. Emerging research implicates the immune system and inflammation in HD pathogenesis. Recent investigations reveal immune cells and lymphatic networks within the meninges, challenging their conventional role solely as a protective CNS barrier. Meningeal immune cells are increasingly recognized for their role in normal brain function and various neurological disorders. However, investigations into meningeal immunity in the context of H

Parkinson's disease is a progressive neurodegenerative disorder characterized by the appearance of motor and non-motor symptoms, resulting from the depletion of dopamine due to the degeneration of dopaminergic neurons. Unfortunately, there is currently no definitive test to confirm the diagnosis and no curative treatment for this disease.Our Epidemiological Study of the disease in Mauritania revealed several important findings. Age is a key factor in the incidence of the disease, with a significant increase in cases in individuals aged between 50 and 70. Parkinson's disease is also male-domina