Topic: neuroscience research

The Miniscope Project -- an open-source collaborative effort—was created to accelerate innovation of miniature microscope technology and to increase global access to this technology. Currently, we are working on advancements ranging from optogenetic stimulation and wire-free operation to simultaneous optical and electrophysiological recording. Using these systems, we have uncovered mechanisms underlying temporal memory linking and investigated causes of cognitive deficits in temporal lobe epilepsy. Through innovation and optimization, this work aims to extend the reach of neuroscience research

Since decades ago, biologists have recognized the existence of tradeoffs in biological systems (e.g., [1]). Yet, the first study that borrowed the idea of Pareto-optimality to analyze tradeoffs in biological systems was published in 1995 [2]. In 2008, following [2], it was hypothesized in [3] that Pareto-optimality, which has been used by engineers for many years, should prove to also be significant to the understanding of natural systems. It was also argued in [3] that terminologies such as multi-objective optimization, which are associated with the Pareto principle, should be carefully revis