Topic: posterior parietal cortex

The neural correlates of decision-making have been investigated extensively, and recent work aims to identify under what conditions cortex is actually necessary for making accurate decisions. We discovered that mice with distinct cognitive experiences, beyond sensory and motor learning, use different cortical areas and neural activity patterns to solve the same task, revealing past learning as a critical determinant of whether cortex is necessary for decision tasks. We used optogenetics and calcium imaging to study the necessity and neural activity of multiple cortical areas in mice with diffe

Restoring hand function is a top priority for individuals with tetraplegia. This challenge motivates considerable research on brain-computer interfaces (BCIs), which bypass damaged neural pathways to control paralyzed or prosthetic limbs. Here, we demonstrate the BCI control of a prosthetic hand using intracortical recordings from the posterior parietal cortex (PPC). As part of an ongoing clinical trial, two participants with cervical spinal cord injury were each implanted with a 96-channel array in the left PPC. Across four sessions each, we recorded neural activity while they attempted to pr

Introduction and Objective: The hypothesis that language-cognitive system interactions play a role in understanding domain-specific semantic terms is supported by a few neurophysiological studies, mainly on the motor cortex. Our goal was to assess if visuospatial coding affects the semantic comprehension of space-related words differently for peripersonal and extrapersonal space, and the causal role of the posterior parietal cortex (PPC).Methods: Utilizing Unity3D and Oculus Rift S, a virtual reality setup displayed 3D words at peripersonal (60 cm) and extrapersonal (120 cm) space. Participant