Topic: probabilistic inference

For animals to navigate an uncertain world, their brains need to estimate uncertainty at the timescales of sensations and actions. Sampling-based algorithms afford a theoretically-grounded framework for probabilistic inference in neural circuits, but it remains unknown how one can implement fast sampling algorithms in biologically-plausible spiking networks. Here, we propose to leverage the population geometry, controlled by the neural code and the neural dynamics, to implement fast samplers in spiking neural networks. We first show that two classes of spiking samplers---efficient balanced spi

Sensory cortices display a suite of ubiquitous dynamical features, such as ongoing noise variability, transient overshoots, and oscillations, that have so far escaped a common, principled theoretical account. We developed a unifying model for these phenomena by training a recurrent excitatory-inhibitory neural circuit model of a visual cortical hypercolumn to perform sampling-based probabilistic inference. The optimized network displayed several key biological properties, including divisive normalization, as well as stimulus-modulated noise variability, inhibition-dominated transients at stimu

Efficient behavior in our noisy and ambiguous world calls for the strategic use of the arising uncertainty by probabilistic inference [1]. Probabilistic inference in complex dynamic environments is challenging as it requires tracking not only individual latent variables but also the interactions among them. As a result, a neural circuit that optimally encodes these variables would need to be recurrently wired to relay information between them via feedback connections [2]. Given the additional cost of evolving and maintaining these feedback connections, we sought the circumstances under which t