Topic: quantitative imaging

Develop data-based mechanistic models of mouse and human tissue development. Integrate quantitative imaging with mathematical simulations, collaborate with experimentalists and contribute to open-source tools and teaching. This salaried doctoral position is based in Basel and accepts applications on a rolling basis until filled. Apply through the ETH online recruitment portal.

Tissue folding is a ubiquitous shape change event during development whereby a cell sheet bends into a curved 3D structure. This mechanical process is remarkably robust, and the correct final form is almost always achieved despite internal fluctuations and external perturbations inherent in living systems. While many genetic and molecular strategies that lead to robust development have been established, much less is known about how mechanical patterns and movements are ensured at the population level. I will describe how quantitative imaging, physical modeling and concepts from network science