Topic: raphe

Execution and adaptation of motor behaviors require the interaction of networks of neurons in the spinal cord, sensory ganglia, and the brain. Sensory input from the skin and muscles is relayed to the dorsal horn of the spinal cord. Neurons in the dorsal and intermediate spinal cord integrate and convey the processed sensory feedback to the ventral premotor network to initiate or correct motor actions or to specialized brain areas for perception and long-term adaptation. Although the identity and post-synaptic targets of spinal ascending projection neurons have started to be characterized, we

When larval zebrafish experience whole-field visual motion, as in the random-dot task, they swim in the direction of motion - an innate behavior enabling animals to maintain position in moving water. This behavior is well-explained by the same drift-diffusion algorithm that captures human and primate behavior in analogous random-dot paradigms. We previously proposed a hypothetical circuit model that implements this algorithm via a recurrent integrator circuit in the zebrafish hindbrain that accumulates noisy visual evidence and excites downstream motor circuits after overcoming competitive inh