Replay sequences

Much is known about the neural representations of current environmental location and direction within the hippocampal formation, but use of such a “cognitive map” requires the online representation of desired locations and how to get there, and the neural basis for this function has been more elusive. I will discuss how “theta sweeps” of place and grid cell firing encode the current location (at early phases of each theta cycle) while, at later phases, sampling around the forward direction during exploration and indicating the direction to desired locations during goal-directed navigation. I w

…slices to predict temporal stimuli and replay sequences. The conversation also addresses the relationship between AI and neuroscience, agreements and tensions between physics and neuroscience about time, and his objections to integrated information theory as an account of consciousness.

…the animal’s own position but also replaying goal-directed paths. Whether and how spatially-tuned neurons in the hippocampus can also discriminate behavioral contexts targeting different destinations remain, however, unclear.By using a navigation task that requires frequent updates in goal locations, we found that, while a majority of place cells in the hippocampal CA1 maintained the s

…in the hippocampus take part in replay sequences, time-compressed reactivations of trajectories through space the animal has previously explored. These replay sequences have been proposed to be a form of memory for previously experienced places. I will present work exploring how these replays appear and change with experience. By recording from large ensembles of hippocampal neurons as rats explored novel and familiar linear tracks in various experiments, we found that hippocampal replays appear after a single experience and slow d