Develop a practical foundation for handling and interpreting next-generation sequencing data. This workshop-style winter school begins with Linux, cloud computing and sequence-quality assessment, then uses containers for reproducible analysis. Exercises cover short- and long-read genome assembly, assembly evaluation, annotation and visualisation, followed by phylogenetics, phylogenomics, RNA-seq processing and differential expression. Examples compare Illumina, Nanopore and PacBio data across biological systems and experimental designs. Live online, 8–12 February, 14:00–20:00 Europe/Berlin (C
In Bio-Informatics and Biology
Much development has been directed toward improving the performance and automation of spike sorting. This continuous development, while essential, has contributed to an over-saturation of new, incompatible tools that hinders rigorous benchmarking and complicates reproducible analysis. To address these limitations, we developed SpikeInterface, a Python framework designed to unify preexisting spike sorting technologies into a single codebase and to facilitate straightforward comparison and adoption of different approaches. With a few lines of code, researchers can reproducibly run, compare, and