Topic: respiration

In this study, we explore the influence of airway modulation on the phenomenon of breath-brain coupling in humans. Utilizing magnetoencephalography and concurrent breathing measurements, we conducted a comparative analysis of Respiratory-Modulated Brain Oscillations (RMBOs) during oral and nasal breathing. Our findings suggest an association between nasal breathing and the generation of RMBOs. This observation hints at the physiological mechanisms linking respiration and brain activity, highlighting the role of nasal breathing in modulating brain functions. Our work contributes to our understa

Breathing, a quintessential physiological process, has garnered increasing attention for its profound impact on brain function. Recent investigations have established the pivotal role of respiration in orchestrating rhythmic neuronal activity, facilitated by two primary pathways: efferent intracerebral projections from rhythm generators and reafferent inputs via the olfactory pathway. This intricate interplay between respiration and limbic neuronal dynamics has spurred hypotheses regarding the potential role of breathing in supporting the synchronization of limbic circuits.Yet, elucidating the

Respiration shares strong functional links with the brain, influencing perception, emotions and cognition. In turn respiration is modulated by sensory stimuli, attention and vigilance states. To explore this intricate brain-body relationship, we performed intranasal pressure recordings in freely-moving mice paired with extracellular recordings in the CA1 region of the hippocampus to precisely detect Wake, non-REM and REM sleep epochs. We characterized different respiratory cycle features between vigilance states and uncovered unexpected breathing dynamics at transitions between them. To show h

Neural activity and bodily functions are inherently rhythmic and related to each other. Hippocampal sharp-wave ripples (SPW-Rs) and dentate spikes (DSs) supporting memory consolidation are most abundant during sleep, especially during non-rapid-eye-movement (NREM) sleep. They also seem to aggregate to a certain phase of the breathing cycle during natural sleep in mice. Here, we aimed to study if the interhemispheric synchrony of SPW-Rs and DSs is affected by neural and bodily state. We recorded dorsal hippocampal local-field potentials and respiration for several hours under urethane anesthesi

Vocal communication is of utmost importance in human and animal interactions. However, little is known regarding the physiological states underlying vocal signaling. It was thought for decades that the ability to decouple emotional states from the vocal output, indicating volitional control of vocalizations, was a clear distinction between humans and non-human primates, whose affective state was supposed to exclusively drive vocal behavior. Additionally, human speech involves a very sophisticated control of breathing with multiple units of sound produced during extended expirations. Novel evid