Topic: sensory cortices

To build an appropriate representation of the sensory stimuli around the world, neural circuits are wired according to both intrinsic factors and external sensory stimuli. Moreover, the brain circuits have the capacity to rewire in response to altered environment, both during early development and throughout life. In this talk, I will give an overview about my past research in studying the dynamic processes underlying functional maturation and plasticity in rodent sensory cortices. I will also present data about the current and future research in my lab – that is, the synaptic and circuit me

Our research team runs several related projects studying the cellular and molecular mechanisms involved in the development of axonal connections in the brain. In particular, our aim is to uncover the principles underlying thalamocortical axonal wiring, maintenance and ultimately the rewiring of connections, through an integrated and innovative experimental programme. The development of the thalamocortical wiring requires a precise topographical sorting of its connections. Each thalamic nucleus receives specific sensory information from the environment and projects topographically to its corres

Interacting with the environment to process sensory information, generate perceptions, and shape goal-directed behavior engages neural networks in brain areas with highly varied representations, ranging from unimodal sensory cortices to higher-order association areas. These networks form and undergo considerable and potentially area-specific refinement over development. However, recent work suggests a much greater degree of commonality in the functional organization of networks across such diverse cortical areas during early development. It is currently unknown whether this initially common st