Topic: Sensory-evoked activity

Sensory perception allows us to receive and integrate information from the environment, a process that starts right from birth. Indeed, newborns can interact with their environment and perform sensorimotor tasks soon after birth, without any previous experience of patterned sensory input. Understanding how neurons assemble into circuits that developmentally prepare to encode visual information accordingly to arousal states is still poorly understood and is likely to provide critical insight not only into how these circuits function, but also how they malfunction in various neurological conditi

The Habenula (Hb), an evolutionarily conserved diencephalic nucleus crucial for adaptive behaviors, undergoes sequential neurogenesis in developing zebrafish, forming organized neuronal ensembles. Despite the increasing complexity of adaptive behaviors observed in developing zebrafish, the contribution of Hb neurogenesis to sensory and limbic integration remains unclear. Using in vivo birth-dating and functional brain imaging, we examined sensory-evoked activity in Hb neurons born at different developmental stages and their telencephalic input regions. Molecular markers identified distinct Hb