Topic: single-cell sequencing

Investigate resistance to KRAS inhibition across genetically distinct pancreatic cancers. The doctoral project studies tumour-cell and stromal mechanisms, including fibroblast effects, using organoid transplantation, mouse models, CRISPR, single-cell sequencing, flow cytometry and spatial methods. It seeks evidence for rational combination therapies and begins in October 2027.

Tom Nowakowski explains lineage barcoding and single-cell sequencing approaches for reconstructing neural stem-cell family trees and early wiring programs in developing mouse and human brains.

Investigate immune regulation in sepsis, particularly neuroimmune and interorgan communication, using computational analyses of bulk and single-cell sequencing datasets. The project is funded by FAPESP and is expected to start in November 2026. The advertisement lists 31 October 2026 as its application deadline and states that review starts immediately and continues until the position is filled. Submit a CV, research-interest cover letter and contact details for two references to the investigator listed on the official page.