Topic: spatio-temporal dynamics

Basket cells are key GABAergic inhibitory interneurons that target the somata and proximal dendrites, enabling efficient control of the timing and rate of spiking of their postsynaptic targets. In all cortical circuits, there are two major types of basket cell that exhibit striking developmental, molecular, anatomical, and physiological differences. In this talk, I will discuss recent results that reveal the tightly coupled complementarity of these two key microcircuit regulatory modules, demonstrating a novel form of brain-state-specific segregation of inhibition during spontaneous behavior,

Emotion processing is thought to be impaired in autism and linked to atypical visual exploration and arousal modulation to others faces and gaze, yet evidence is equivocal. We propose that, where observed, atypical socioemotional processing is due to alexithymia, a distinct but frequently co-occurring condition which affects emotional self-awareness and Interoception. In study 1 (N = 80), we tested this hypothesis by studying the spatio-temporal dynamics and entropy of eye-gaze during emotion processing tasks. Evidence from traditional and novel methods revealed that atypical eye-gaze and emot

Accumulating evidence from electrocorticogram (ECoG) recordings and imaging challenge traditional views of brain oscillations as spatially stationary periodic sources. Understanding the spatio-temporal dynamics of cortical activity requires novel measurement and analysis methodologies. We recorded broadband local field potential (LFP) across the whole neocortex in freely behaving rats using high-density flexible surface arrays using active transistors. 3D tracking and spatio-spectral analysis of recordings over long sessions enabled automatic and accurate brain and behavioral states segmentati