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Topic: stabilized supralinear network

Seminar
2 seminars

In Applied Mathematics and Biology

Seminar · Computational Neuroscience

The balance of excitation and inhibition and a canonical cortical computation

Yashar Ahmadian · Cambridge, UK

Wed, Apr 27, 2022 · 05:00 UTC

Excitatory and inhibitory (E & I) inputs to cortical neurons remain balanced across different conditions. The balanced network model provides a self-consistent account of this observation: population rates dynamically adjust to yield a state in which all neurons are active at biological levels, with their E & I inputs tightly balanced. But global tight E/I balance predicts population responses with linear stimulus-dependence and does not account for systematic cortical response nonlinearities such as divisive normalization, a canonical brain computation. However, when necessary connectivity co

Seminar · Computational Neuroscience

A theory for Hebbian learning in recurrent E-I networks

Samuel Eckmann · Gjorgjieva lab, Max Planck Institute for Brain Research, Frankfurt, Germany

Thu, May 20, 2021 · 16:30 UTC

The Stabilized Supralinear Network is a model of recurrently connected excitatory (E) and inhibitory (I) neurons with a supralinear input-output relation. It can explain cortical computations such as response normalization and inhibitory stabilization. However, the network's connectivity is designed by hand, based on experimental measurements. How the recurrent synaptic weights can be learned from the sensory input statistics in a biologically plausible way is unknown. Earlier theoretical work on plasticity focused on single neurons and the balance of excitation and inhibition but did not cons