Lead the medical and clinical development strategy for Beam’s metabolic disease franchise. The role shapes clinical plans and study protocols for base editing therapies, oversees ongoing trials and patient safety, and coordinates clinical and regulatory strategy. Responsibilities include mentoring physicians and clinical scientists and working with research teams on subsequent therapeutic programmes. This hybrid role requires residence within commuting distance of Cambridge, Massachusetts.
Topic: study protocols
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Job · Clinical Pharmacology
Fidelity and Replication: Modelling the Impact of Protocol Deviations on Effect Size
Michelle Ellefson · Faculty of Education, University of Cambridge
Cognitive science and cognitive neuroscience researchers have agreed that the replication of findings is important for establishing which ideas (or theories) are integral to the study of cognition across the lifespan. Recently, high-profile papers have called into question findings that were once thought to be unassailable. Much attention has been paid to how p-hacking, publication bias, and sample size are responsible for failed replications. However, much less attention has been paid to the fidelity by which researchers enact study protocols. Researchers conducting education or clinical tria
Tue, Feb 28, 2023 · 15:00 UTC