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Topic: systemic inflammation

Seminar
1 seminar

In Biology and Developmental Biology

Seminar · Developmental Neuroscience

Role of Oxytocin in regulating microglia functions to prevent brain damage of the developing brain

Olivier Baud · Division of Neonatology, Department of Pediatrics, Development and growth laboratory, University of Geneva, Switzerland

Tue, Feb 2, 2021 · 12:15 UTC

Every year, 30 million infants worldwide are delivered after intra-uterine growth restriction (IUGR) and 15 million are born preterm. These two conditions are the leading causes of ante/perinatal stress and brain injury responsible for neurocognitive and behavioral disorders in more than 9 million children each year. Both prematurity and IUGR are associated with perinatal systemic inflammation, a key factor associated with neuroinflammation and identified to be the best predictor of subsequent neurological impairments. Most of pharmacological candidates have failed to demonstrate any beneficia