Lead lipid-nanoparticle formulation, characterisation and process scale-up for investigational gene-editing therapies. Responsibilities span mixing and tangential-flow filtration from bench to GLP/GMP scale, process optimisation, external manufacturing transfer and contributions to regulatory CMC documentation. The position connects delivery technology with manufacturable drug products and involves collaboration with research, platform and therapeutic teams. The advertised annual base salary is USD 145,000–161,000, with additional incentive eligibility.
Job · Chemistry
Associate Scientist/Engineer II Technology, Development and Operations - Chemistry
Deadline not stated
Develop, optimise and transfer RNA manufacturing processes supporting Prime Editing programmes. Hands-on work includes solid-phase synthesis of long guide RNAs, chromatography, tangential-flow filtration and lyophilisation across scales, alongside GLP/GMP material production, analytical interpretation and technical documentation. The position works across research, technical development, external manufacturing and quality. The advertised annual base salary is USD 80,000–90,000, with additional incentive eligibility.