Associate Scientist/Engineer II Technology, Development and Operations - Chemistry
Chemistry, Synthetic Chemistry, Bioprocess Engineering and position at Prime Medicine
About
Develop, optimise and transfer RNA manufacturing processes supporting Prime Editing programmes. Hands-on work includes solid-phase synthesis of long guide RNAs, chromatography, tangential-flow filtration and lyophilisation across scales, alongside GLP/GMP material production, analytical interpretation and technical documentation. The position works across research, technical development, external manufacturing and quality. The advertised annual base salary is USD 80,000–90,000, with additional incentive eligibility.
Topics
- Prime Editing
- RNA manufacturing
- long guide RNAs
- solid-phase synthesis
- chromatography
- tangential-flow filtration
- lyophilisation
- GLP
- GMP
- technical documentation
Requirements
BS or MS in biotechnology, engineering, chemistry, biochemistry or a related life science, ideally with at least three years of industry experience after BS or one after MS. Relevant biomolecule process-development and GMP experience; oligonucleotide synthesis or downstream purification is an advantage. The application asks about commuting to the Boston-area office.
Related jobs
- Posted Oct 23, 2026Cambridge, United States
Research Associate, Automation & Assays
Posted Oct 23, 2026Cambridge, United StatesScientist III – Proteome Editor Design / AI BioDesign
Posted Oct 5, 2026Seattle, United States
Open jobs in Chemistry
All jobsAssistant Professor in Chemistry
Closes Jan 1, 2027University of California, Davis · Davis, United StatesPrincipal Scientist, Process Chemistry
Calico · South San FranciscoAssistant or Associate Professor in Synthetic Biology, Biotechnology and Applied Biochemistry
University of Minnesota · Twin Cities, United StatesScientist - Medicinal Chemistry
Amgen · Thousand Oaks, United States
Source: Prime Medicine