Engineer III, mRNA Process Development-Downstream
Bioprocess Engineering, Pharmaceutics and full-time position at CRISPR Therapeutics
About
Develop downstream purification processes for mRNA drug substance and transfer them to external GMP manufacturers. The engineer evaluates chromatography, filtration and concentration operations, develops impurity-clearance strategies and scales processes from laboratory to pilot production. Responsibilities include partner-site technical support and interpretation of manufacturing performance. This full-time position is fully onsite in South Boston, Massachusetts, with partner-site work as required.
Requirements
BS in chemical, biochemical or biological engineering with four to six or more years of relevant industry experience, or MS with two to five or more years. Requires chromatography and tangential-flow filtration, scale-up, process transfer to external manufacturers and experimental design experience.
Topics
- mRNA drug substance
- downstream purification
- chromatography
- filtration
- concentration
Source: CRISPR Therapeutics