Topic: thrombosis

Two separate one-day workshops connect laboratory testing with clinical interpretation through expert presentations, practical cases and interactive discussion. The Haemostasis & Thrombosis Workshop on 10 November covers von Willebrand factor assays, rare bleeding disorders, variability in point-of-care coagulation tests, viscoelastic testing and clot curves. Sessions also address heparin-induced thrombocytopenia, ADAMTS13 and thrombotic thrombocytopenic purpura, endothelial activation, platelet testing and external quality assurance. The Haemoglobinopathy Workshop on 12 November examines

Hosted by the American Society of Hematology, this meeting connects basic and translational blood research with clinical practice. Scientific sessions examine how genomic diagnostics, long-read sequencing and three-dimensional marrow models improve understanding of inherited disorders; how clonal selection and immune escape drive marrow failure; and how RNA regulation offers therapeutic targets in leukemia. AI-assisted flow cytometry, spatial multi-omics and epigenomic profiling link molecular mechanisms to diagnosis and risk stratification. Further sessions investigate stem-cell niches and im

Clinical intervention for ischemic stroke patients is limited to the acute phase, leaving ~80% of stroke patients without effective pharmacological intervention and unsatisfactory neurological outcome. Therefore, subacute therapeutics that resolve thrombosis and inflammatory processes to support tissue recovery are urgently in need. Plasma kallikrein (PK), a member of the kallikrein-kinin-system, promotes vascular damage, inflammation, and thrombosis. We hypothesize that prolonged PK activation determines stroke severity and impairs tissue recovery. Thus, wild-type mice were subjected to 60 mi