Visual feedback

…finger under direct or mirror-reversed visual feedback to create a conflict between visual and somatosensory inputs. In this context, increased reliance on somatosensory input compromises movement accuracy. Based on the hypothesis that tactile cues contribute to guiding hand

Control of cursor on a PC monitor using a joystick is a common paradigm to elucidate the neural mechanisms of visuomotor skill learning and performance in human and non-human primates. However, this paradigm, even for reaching targets in one-dimensional space, has not been available for rodents yet. In this work, we present an ergonomic head fixation apparatus for Wistar rats to control a cursor on a PC monitor by operating two levers for acquiring stationary targets. All six axes of the apparatus, composed of V-slot aluminum profiles and 3D-printed parts, are easily adjustable according to th

Performing goal-directed behaviors in an uncertain environment requires organisms to continuously evaluate the sensory consequences of their motor actions and fine-tune them to ultimately reach the goal. This evaluation involves a comparison between the predicted and actual sensory change following a movement and implementing corrective movements if there is a mismatch between the two. However, details about the neural implementation of this comparison and correction are unclear. We study this paradigm in larval zebrafish using a virtual reality setup. We first “train” the fish such that they

…The MC model receives sensory feedback and delivers muscle excitations to anatomically accurate musculoskeletal models to produce experimentally observed movements. The se

When presented with identical task conditions across multiple trials, the brain produces variable patterns of neural activity. This neural variability stems from many sources, one of which is fluctuations in internal states (e.g., arousal, attention, and motivation). Neural variability may reflect changes in these internal cognitive factors and can influence our perceptual and decision-making abilities. For instance, when tasked with shooting consecutive free throws on a basketball court, we may experience changes in our arousal, and our minds might wander. Such trial-to-trial variability can