Anatomy ePosters

Sensory information is first processed by various thalamic nuclei before reaching the pallium in amniotes, where it is used for higher-order computations such as integrating diverse sensory information that can be utilized to form associations. In teleost fish, the dorsal thalamic nuclei, believed to be analogous to…

The dynamic interplay of inhibitory and excitatory neurons drives the cortical functional repertoire. In the mammalian neocortex, inhibitory neurons are diverse. They are characterized by a variety of cellular attributes that enable their specialized roles in regulating information processing. It is increasingly clear…

Computational models have been seminal in expanding our understanding of how neural, biomechanical, or physical elements can give rise to behavior. With the forthcoming emergence of nearly complete connectomes of the central nervous system, musculature, and biomechanics of Drosophila, it is only now possible to…

The nervous system scales with animal size, maintaining function while minimizing wire. In contrast to most animal organs, which scale through the proliferation of dividing cells of similar size, brains expand by modulating the size of non-dividing neuronal cells to innervate space during development. As a result,…

The interplay of the calcium concentration and the anatomical structure at the presynaptic zone of presynaptic boutons is an important challenge of the relationship of form and function in (computational) neuroscience. A simple model system to study such basic effects is the neuromuscular junction of the Drosophila…

The fusiform gyrus (FG) in the human brain is essential for higher cortical functions such as recognizing faces and human bodies [1, 2]. Though, the relationship of its structural and functional decompositions in the anterior portion is yet to be better understood [3]. Here, the anterior FG was investigated in ten…

Glial cells show great diversity and differ in terms of their functional roles. Microglia, oligodendrocytes, and astrocytes interact with neurons and thus ensure the functionality of the neurons. However, little is known about how they interact with different neuronal cell types. We investigate glial and neuronal…

Comparative neuroanatomy has been a challenging research field, even with the methodological innovations in recent years. In this context, cortical surface reconstructions emerged as a new venue to provide further insights on brain morphology, but they are mostly limited to humans and a few other primates, hindering a…

The lymphatic vessels (LVs) contribute to tissue homeostasis and function by facilitating the clearance of excess fluid and macromolecules from the interstitial tissue of the brain. Various routes for the extracranial transport of LV drainage from the brain parenchyma to the deep cervical lymph nodes were described.…

Brain atlases like the Allen Mouse Brain Common Coordinate Framework (CCFv3) are essential tools to guide the integration of different sources of neuroscience data. In this study, we introduce a novel method for curating brain atlas regions that leverages the strength of Houdini and Python software. This approach…

Background: Folate supplementation throughout pregnancy is recommended to support foetal and early postnatal brain development. The exact effect of folate on cerebellar development is unknown. This study looked at how maternal folate consumption impacts the structural development of the offspring's cerebellar…

Aims. As the most abundant cells in the central nervous system, astrocytes include two morphological forms (protoplasmic and fibrous), providing structural and functional support for the neurons. Their number and cytoarchitecture are frequently affected by neurodegenerative diseases and aging. The scope of this study…

Over recent years, there has been an increasing need for a better understanding of the identity and the roles of astrocytes and their involvement in cognitive abilities. Indeed, they play a crucial role in brain functions, they show primate-specific features, and they are relevant in several diseases. Investigations…

Astrocytes display complex morphology ranging from multiple main processes stemming from the soma to endfeet and a myriad of leaflets that are in close contact with synapses and other cellular structures. This extended feature, which is heterogeneous across brain regions and physiological states, is pivotal to…

The lateral septum (LS) integrates diverse subcortical and cortical inputs to generate appropriate affective behavioral responses related to fear, reward, social behaviors, and memory. Contrary to the medial septum (MS) the LS is considered an entirely GABAergic nucleus where neurons express a plethora of GABAergic…

The salamander axolotl (Ambyostoma mexicanum) is a model for studying nervous system evolution, development, and regeneration. Axolotls can regenerate injuries to the central and peripheral nervous system making them an ideal model to study formation and regeneration of neuronal circuits. Tools to visualize and…

The generating mechanism for the gyrification of the mammalian cerebral cortex remains a central open question in neuroscience. Although many models have been proposed over the years, very few were able to provide empirically testable predictions. In this paper, we assume a model in which the cortex folds for all…

How does the motor cortex (MC) achieve generalizable and purposeful movements from the complex non-linear musculoskeletal system? This understanding can help us uncover how does the cortical activity relates to the movement. To elucidate this relationship, we build a model of the MC with realistic properties. To mimic…

The apparent motion of features in a visual scene — optic flow — provides rich information about the animal’s self-motion and its environment [Gibson 1950]. An animal estimates the optic flow with motion sensitive neurons. In flies, the T4/T5 neurons encode small-field directional motion signals by sampling…