3 results
Nature staff discuss an AI tool for assessing the effects of nine billion human genetic mutations, followed by research challenging assumptions about Bunsen burners and contamination near laboratory work areas. This episode is part of Nature Podcast’s Briefing Chat series and is available from the publisher on Acast.
Published Sep 11, 2026 · 16 min
Vincent Racaniello, Kathy Spindler and Brianne Barker discuss research using generative AI to design complete bacteriophage genomes, including reported viable phages active against antibiotic-resistant bacteria. They also examine a study linking recombinant shingles vaccination with lower cardiovascular-event risk. The discussion connects genome modelling, experimental virology and vaccine research, alongside listener letters and weekly selections.
Hosted by Vincent Racaniello, Brianne Barker
Published Sep 6, 2026 · 1 h 38 min
Mariana Kneppers, Mason Wakley and Neil Withers discuss two questions about genetic information. They examine AlphaGenome, a machine learning model designed to predict molecular effects of DNA variants across long sequences, and consider its potential use in genetics research. The episode then turns to the RNA world hypothesis: the proposal that RNA-based systems preceded DNA genomes and cells during the early history of life. The discussion links contemporary tools for studying the genome with chemical questions about life's beginnings.
Hosted by Mariana Kneppers
Published Feb 11, 2026