Fri Nov 20 · 02:00 UTC · Seminarmalaria
ASP Online Seminar Series: Friday 20 November at 1pm AEDT
Josh Levendis, Alex Harris · University of Melbourne · Online
Josh Levendis examines how N6-methyladenosine RNA modification controls gene expression in Plasmodium falciparum. Nanopore direct RNA sequencing and GLORI-seq reveal enrichment near transcript ends. Inducible mislocalisation of methyltransferase depletes this modification and produces readthrough and chimeric transcripts, implicating methylation in correct polyadenylation and transcription…