29 results
Study genetic determinants of climate resilience in algae through the Golden Genome project supported by Revive and Restore. The work involves constructing insertional deletion libraries in microalgae, developing transformation approaches for the kelp Ecklonia radiata, and maintaining and cryopreserving algal cultures. The project combines molecular methods…
Develop new AI and machine-learning methods for biological research in a tenure-track appointment shared by UC Berkeley’s EECS department and Center for Computational Biology. Topics include predicting cellular responses to genetic, molecular and environmental perturbations, molecular interactions, genotype-to-phenotype relationships, genome and biomolecule…
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Investigate development and organisation of the visual system using single-cell and spatial molecular profiling. The postdoctoral work combines multi-omics, viral engineering and computational modelling. The priority review date has passed; later applications are considered if the vacancy remains unfilled, through the final date shown.
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Sibylle Vonesch’s Laboratory for Genome Editing and System Genetics seeks a computational postdoctoral researcher for high-throughput studies of genetic variation. MAGESTIC links thousands of precisely engineered CRISPR variants to DNA barcodes, enabling measurement of genotype–phenotype relationships across large cell populations. The project examines how…
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Develop new gene insertion approaches and engineered immune-cell therapies in the CRISPR-X research team. The scientist designs genome editing experiments and CAR-T constructs, evaluates molecular and cellular outcomes, and develops translational assays for new disease indications. Methods include cloning, quantitative and digital PCR, sequencing and…
Synthesise, purify and characterise modified oligonucleotides for gene editing and targeted delivery research. The role uses automated solid-phase synthesis, preparative chromatography, LC-MS and bioconjugation to produce RNA/DNA reagents and small-molecule or antibody conjugates for experimental studies. This full-time laboratory role is fully onsite in…
Develop computational approaches to understand Gene Writing biology and assess genomic safety. The scientist works with experimental teams on study design and multi-omics analysis, builds reproducible sequencing pipelines and interprets molecular data for research and preclinical programmes. The Somerville role requires onsite work two to three days per…
Provide medical oversight for early clinical studies of Tessera’s Gene Writing therapies for hematologic disease. Work includes reviewing eligibility, safety findings and clinical laboratory data, advising investigators, contributing to study designs and interpreting efficacy and biomarker results. The role supports development in indications such as sickle…
Guide Prime Editing programmes from preclinical research into human studies. The medical director develops trial strategies and protocols, monitors participant safety and clinical data, and works with research colleagues on translational biomarkers. Responsibilities also include investigator engagement, regulatory discussions and scientific presentations.…
Lead the medical and clinical development strategy for Beam’s metabolic disease franchise. The role shapes clinical plans and study protocols for base editing therapies, oversees ongoing trials and patient safety, and coordinates clinical and regulatory strategy. Responsibilities include mentoring physicians and clinical scientists and working with research…
A January–June 2027 technical operations placement supporting equipment and process validation for gene editing medicines. The student reviews scientific and engineering information, evaluates manufacturing data and prepares technical summaries for cross-functional teams supporting hematology and liver programmes. Based in Durham, North Carolina, the role…
Join the mRNA Science team for a January–June 2027 placement in Cambridge, Massachusetts. Experiments compare mRNA sequences and chemical modifications using mammalian cell culture, transfection, protein-expression measurements and biochemical assays. The student generates and interprets experimental data and may also contribute to cloning, plasmid…
A January–June 2027 placement developing and optimising gene editing systems for therapeutic programmes. Work includes generating reagents and small-scale mRNA preparations, maintaining mammalian cells, transfecting cells, isolating genomic DNA and preparing samples for sequencing. The student collaborates with research scientists on experimental design,…
Support clinical development of gene and base editing therapies through pharmacokinetic, pharmacodynamic and quantitative systems models. The role connects nonclinical and clinical analyses to study design, regulatory documents and programme decisions, and helps develop the clinical pharmacology function. It can emphasise pharmacometrics or combine…
Join the Mukhopadhyay Group and DOE m-CAFEs project to engineer plant-associated microbes and investigate sorghum root ecosystems. The research combines genetics, proteomics, metabolomics and functional genomics to study microbial stress responses, biofilms, horizontal gene transfer, community stability and root colonization. Responsibilities include…
Produce and characterize viral tools for brain-cell labelling, circuit tracing and functional manipulation at the Allen Institute. The Molecular Genetics Viral Technology team works with AAV, lentiviral and rabies-virus preparations. Responsibilities include molecular cloning, DNA/RNA purification, cell culture, virus production and titration, and in vitro…
The Molecular Genetics department of the Allen Institute's Brain Science accelerator defines cell types in the mouse nervous system with single-cell genomics and builds high-precision genetic tools to identify, monitor and manipulate distinct neuronal cell types. The Research Associate I supports the Genetic Tools Pipeline team, which generates and…
Xin Jin's lab at Scripps Research investigates how physiology and genetics converge to shape the developing brain, combining in vivo CRISPR screening with single-cell multi-omics, spatial genomics and chemical-biology tools. The Research Technician III supports studies of brain development and neurodevelopmental disease mechanisms: mouse handling, colony…
Develop synthetic biological tools that make multicellular behaviour predictable and programmable within the Cell Science accelerator. Pursue questions about synthetic tissues and cell behaviour, using stem-cell engineering, high-content microscopy, molecular engineering and quantitative modelling. Collaborate with scientists and project specialists. The…
Brain Health is a new global collaborative research initiative designed to accelerate understanding of human brain diseases through large-scale human tissue analysis, open science, AI-enabled disease modeling, and translational platform technologies. Building on foundational advances in human brain cell atlases, quantitative neuropathology, single-cell and…
We seek a Scientist I to build the computational backbone of a lab-in-the-loop platform that designs and validates synthetic enhancers for precision cell-type targeting in the brain. In this cycle, model-designed sequences are tested experimentally, and the results retrain the next round of models. You will contribute to an open-source codebase for…
The Research Luke Harland is establishing a new research group based in the Loke Centre for Trophoblast Research within the Department of Physiology, Development and Neuroscience at the University of Cambridge. The group investigates how specialised blood and vascular cell types arise during mammalian development and uses this knowledge to generate defined…
Join the Wallrath and Drack laboratories to investigate human vision disorders and develop experimental therapeutic approaches. The work combines mouse and cellular models, AAV gene therapy, CRISPR or siRNA perturbations, microscopy, biochemical assays and electrophysiology, with connections to clinical research. This full-time postdoctoral position remains…
Lead research linking focused ultrasound, synthetic biology and cancer immunotherapy in Nate Yoon’s RPBS Lab. Projects include ultrasound-responsive gene circuits, immune-cell mechanotransduction and acoustic tools for imaging and therapy. Mentor students and develop an independent research trajectory in an interdisciplinary engineering environment. The…