Molecular Biophysics ePosters

Memory and learning are significantly influenced by long-term changes in synaptic strength, though the exact molecular mechanisms remain unclear. The postsynaptic density (PSD) is a critical component for storing and organizing synaptic long-term changes. The PSD itself is organized into complex nano-clusters, which…

Low-intensity ultrasound neuromodulation is a rapidly emerging technology due to its non-invasiveness and millimeter-scale precision. Despite numerous experimental settings demonstrating that ultrasonic waves can modulate the neural activity in different brain areas, the interaction between the ultrasonic source and…

Automated voltage-clamp recordings from 40 voltage-gated potassium (Kv) channels [1] revealed the inherent kinetic heterogeneity of some Kv types expressed in the brain (e.g. Kv1.3). A model capable of capturing the kinetic Kv heterogeneity requires both fixed model features shared between cells, and the ability to…