Savina Cammalleri discusses extending DISCO, a digital microfluidic platform for single-cell omics, to protein analysis. The work uses controlled handling of individual cells and samples to make proteomic measurements more efficient and scalable. The presentation considers how a flexible microfluidic approach can support studies of variation between cells and the molecular processes underlying that variation. Its goal is to broaden the experimental tools available for biological measurements at single-cell resolution. Cammalleri is a doctoral researcher in biomedical engineering at the University of Toronto and conducts her research at the Max Planck Institute for Multidisciplinary Sciences.