Combining two mechanisms to produce neural firing rate homeostasis
Schedule
Friday, June 11, 2021
15:00 UTC
Paul Miller
Prof
Brandeis University
Host: The Neurotheory Forum
Recording
Open recording
Event Information
Recording
Available
Host
The Neurotheory Forum
Duration
70 minutes
Abstract
The typical goal of homeostatic mechanisms is to ensure a system operates at or in the vicinity of a stable set point, where a particular measure is relatively constant and stable. Neural firing rate homeostasis is unusual in that a set point of fixed firing rate is at odds with the goal of a neuron to convey information, or produce timed motor responses, which require temporal variations in firing rate. Therefore, for a neuron, a range of firing rates is required for optimal function, which could, for example, be set by a dual system that controls both mean and variance of firing rate. We explore, both via simulations and analysis, how two experimentally measured mechanisms for firing rate homeostasis can cooperate to improve information processing and avoid the pitfall of pulling in different directions when their set points do not appear to match.
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