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Dr
Executive Vice President and Director of Allen Institute for Brain Science, Seattle, USA
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Schedule
Tuesday, February 23, 2021
11:00 AM Canada/Eastern
Domain
NeuroscienceHost
Ad hoc
Duration
70 minutes
To understand the function of the brain and how its dysfunction leads to brain diseases, it is essential to have a deep understanding of the cell type composition of the brain, how the cell types are connected with each other and what their roles are in circuit function. At the Allen Institute, we have built multiple platforms, including single-cell transcriptomics, single and multi-patching electrophysiology, 3D reconstruction of neuronal morphology, high throughput brain-wide connectivity mapping, and large-scale neuronal activity imaging, to characterize the transcriptomic, physiological, morphological, and connectional properties of different types of neurons in a standardized way, towards a taxonomy of cell types and a description of their wiring diagram for the mouse brain, with a focus on the visual cortico-thalamic system. Building such knowledge base lays the foundation towards the understanding of the computational mechanisms of brain circuit function.
Hongkui Zeng
Dr
Executive Vice President and Director of Allen Institute for Brain Science, Seattle, USA
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