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Low Intensity Rtms Age

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SeminarPast EventNeuroscience

Low intensity rTMS: age dependent effects, and mechanisms underlying neural plasticity

Ann Lohof

Professor

Sorbonne Université, Institut de Biologie Paris Seine

Schedule
Thursday, September 18, 2025

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Thursday, September 18, 2025

12:30 PM Europe/Athens

Host: Athens Neuroscience

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Athens Neuroscience

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Abstract

Neuroplasticity is essential for the establishment and strengthening of neural circuits. Repetitive transcranial magnetic stimulation (rTMS) is commonly used to modulate cortical excitability and shows promise in the treatment of some neurological disorders. Low intensity magnetic stimulation (LI-rTMS), which does not directly elicit action potentials in the stimulated neurons, have also shown some therapeutic effects, and it is important to determine the biological mechanisms underlying the effects of these low intensity magnetic fields, such as would occur in the regions surrounding the central high-intensity focus of rTMS. Our team has used a focal low-intensity (10mT) magnetic stimulation approach to address some of these questions and to identify cellular mechanisms. I will present several studies from our laboratory, addressing (1) effects of LIrTMS on neuronal activity and excitability ; and (2) neuronal morphology and post-lesion repair. The ensemble of our results indicate that the effects of LI-rTMS depend upon the stimulation pattern, the age of the animal, and the presence of cellular magnetoreceptors.

Topics

cellular mechanismscerebellumcortical excitabilitylow intensity rTMSmagnetic stimulationmagnetoreceptorsneural plasticityneuronal activityneuronal morphologynon-invasive brain stimulationpost-lesion repair

About the Speaker

Ann Lohof

Professor

Sorbonne Université, Institut de Biologie Paris Seine

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