SeminarRecording AvailableBrain Imaging

Understanding sensorimotor control at global and local scales

Schedule
Friday, October 9, 2020
11:40 UTC
Kelly Clancy

Dr

DeepMind

Host: SWC Symposium

Recording

Event Information

Recording

Available

Host

SWC Symposium

Duration

70 minutes

Abstract

The brain is remarkably flexible, and appears to instantly reconfigure its processing depending on what’s needed to solve a task at hand: fMRI studies indicate that distal brain areas appear to fluidly couple and decouple with one another depending on behavioral context. We investigated how the brain coordinates its activity across areas to inform complex, top-down control behaviors. Animals were trained to perform a novel brain machine interface task to guide a visual cursor to a reward zone, using activity recorded with widefield calcium imaging. This allowed us to screen for cortical areas implicated in causal neural control of the visual object. Animals could decorrelate normally highly-correlated areas to perform the task, and used an explore-exploit search in neural activity space to discover successful strategies. Higher visual and parietal areas were more active during the task in expert animals. Single unit recordings targeted to these areas indicated that the sensory representation of an object was sensitive to an animal’s subjective sense of controlling it.

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