Artificial Intelligence seminars

Understanding the neural mechanisms of reward-guided learning is a long-standing goal of computational neuroscience. Recent methodological innovations enable us to collect ever larger neural and behavioral datasets. This presents opportunities to achieve greater understanding of learning in the brain at scale, as well as methodological challenges. In the first part of the talk, I will discuss our recent insights into the mechanisms by which zebra finch songbirds learn to sing. Dopamine has been long thought to guide reward-based trial-and-error learning by encoding reward prediction errors. However, it is unknown whether the learning of natural behaviours, such as developmental vocal learning, occurs through dopamine-based reinforcement. Longitudinal recordings of dopamine and bird songs reveal that dopamine activity is indeed consistent with encoding a reward prediction error during naturalistic learning. In the second part of the talk, I will talk about recent work we are doing at DeepMind to develop tools for automatically discovering interpretable models of behavior directly from animal choice data. Our method, dubbed CogFunSearch, uses LLMs within an evolutionary search process in order to "discover" novel models in the form of Python programs that excel at accurately predicting animal behavior during reward-guided learning. The discovered programs reveal novel patterns of learning and choice behavior that update our understanding of how the brain solves reinforcement learning problems.

Synthetic face datasets are increasingly used to overcome the limitations of real-world biometric data, including privacy concerns, demographic imbalance, and high collection costs. However, many existing methods lack fine-grained control over identity attributes and fail to produce paired, identity-consistent images under structured capture conditions. In this talk, I will present FLUXSynID, a framework for generating high-resolution synthetic face datasets with user-defined identity attribute distributions and paired document-style and trusted live capture images. The dataset generated using FLUXSynID shows improved alignment with real-world identity distributions and greater diversity compared to prior work. I will also discuss how FLUXSynID’s dataset and generation tools can support research in face recognition and morphing attack detection (MAD), enhancing model robustness in both academic and practical applications.

In a first part of the talk, I will present Predictive Coding Light (PCL), a novel unsupervised learning architecture for spiking neural networks. In contrast to conventional predictive coding approaches, which only transmit prediction errors to higher processing stages, PCL learns inhibitory lateral and top-down connectivity to suppress the most predictable spikes and passes a compressed representation of the input to higher processing stages. We show that PCL reproduces a range of biological findings and exhibits a favorable tradeoff between energy consumption and downstream classification performance on challenging benchmarks. A second part of the talk will feature our lab’s efforts to explain how infants and toddlers might learn abstract object representations without supervision. I will present deep learning models that exploit the temporal and multimodal structure of their sensory inputs to learn representations of individual objects, object categories, or abstract super-categories such as „kitchen object“ in a fully unsupervised fashion. These models offer a parsimonious account of how abstract semantic knowledge may be rooted in children's embodied first-person experiences.

Recent advances in artificial intelligence have led to new forms of misinformation, including highly realistic “deepfake” synthetic media. We conduct three experiments to investigate how and why retail investors react to deepfake financial news. Results from the first two experiments provide evidence that investors use a “realism heuristic,” responding more intensely to audio and video deepfakes as their perceptual realism increases. In the third experiment, we introduce an intervention to prompt analytical thinking, varying whether participants make analytical judgments about credibility or intuitive investment judgments. When making intuitive investment judgments, investors are strongly influenced by both more and less realistic deepfakes. When making analytical credibility judgments, investors are able to discern the non-credibility of less realistic deepfakes but struggle with more realistic deepfakes. Thus, while analytical thinking can reduce the impact of less realistic deepfakes, highly realistic deepfakes are able to overcome this analytical scrutiny. Our results suggest that deepfake financial news poses novel threats to investors.

Overview of neurosurgery specialty interplay between neurology, psychiatry and neurosurgery. Discussion on benefits and disadvantages of classifications. Presentation of sub-specialties: trauma, oncology, functional, pediatric, vascular and spine. How does an ordinary day of a neurosurgeon look like; outpatient clinic, emergencies, pre/intra/post operative patient care. An ordinary operation. Myth-busting and practical insights of every day practice. An ordinary operation. Hint for research on clinical problems to be solved. The coming ethical frontiers of neuroprosthetics. In part two we will explore the explanatory gap and its significance. We will review the more than 200 theories of the hard problem of consciousness, from the prevailing to the unconventional. Finally, we are going to reflect on the AI advancements and the claims of LLMs becoming conscious

Shannon Vallor examines how code both conceals things of value and provides access to them, using that dual role to investigate what computing hides or reveals about humanity. The lecture challenges the values and purposes embedded in contemporary algorithmic automation. It asks how those aims could be reshaped to support humane futures, bringing philosophical analysis to the design and use of computational systems.

Susan Athey examines how machine learning and digital interventions can help explain and improve workers’ transitions between jobs. One project uses Swedish administrative data to identify groups whose earnings and employment are less resilient after layoffs, revealing substantial differences among workers within the same firms and labour markets. A second line of work uses transformer models and large language models to represent careers and analyse gender wage gaps, identifying settings in which large unexplained differences persist. Two further projects develop and evaluate digital interventions intended to help disadvantaged workers enter expanding occupations in information technology and data science. The lecture connects new methods for measuring labour-market disadvantage with evidence about practical interventions.

Brain Emulation Challenge workshop will tackle cutting-edge topics such as ground-truthing for validation, leveraging artificial datasets generated from virtual brain tissue, and the transformative potential of virtual brain platforms, such as applied to the forthcoming Brain Emulation Challenge.

Brain Emulation Challenge workshop will tackle cutting-edge topics such as ground-truthing for validation, leveraging artificial datasets generated from virtual brain tissue, and the transformative potential of virtual brain platforms, such as applied to the forthcoming Brain Emulation Challenge.

Brain Emulation Challenge workshop will tackle cutting-edge topics such as ground-truthing for validation, leveraging artificial datasets generated from virtual brain tissue, and the transformative potential of virtual brain platforms, such as applied to the forthcoming Brain Emulation Challenge.

Brain Emulation Challenge workshop will tackle cutting-edge topics such as ground-truthing for validation, leveraging artificial datasets generated from virtual brain tissue, and the transformative potential of virtual brain platforms, such as applied to the forthcoming Brain Emulation Challenge.

Dense Associative Memories (Dense AMs) are energy-based neural networks that share many desirable features of celebrated Hopfield Networks but have superior information storage capabilities. In contrast to conventional Hopfield Networks, which were popular in the 1980s, DenseAMs have a very large memory storage capacity - possibly exponential in the size of the network. This aspect makes them appealing tools for many problems in AI and neurobiology. In this talk I will describe two theories of how DenseAMs might be built in biological “hardware”. According to the first theory, DenseAMs arise as effective theories after integrating out a large number of neuronal degrees of freedom. According to the second theory, astrocytes, a particular type of glia cells, serve as core computational units enabling large memory storage capabilities. This second theory challenges a common point of view in the neuroscience community that astrocytes play the role of only passive house-keeping support structures in the brain. In contrast, it suggests that astrocytes might be actively involved in brain computation and memory storage and retrieval. This story is an illustration of how computational principles originating in physics may provide insights into novel AI architectures and brain computation. VVTNS New Year Opening Lecture. Presented in the van Vreeswijk Theoretical Neuroscience Seminar series (formerly WWTNS) on 2025-01-08. Recording duration: 00:49:16.

This webinar convened researchers at the intersection of Artificial Intelligence and Neuroscience to investigate how large language models (LLMs) can serve as valuable “model organisms” for understanding human language processing. Presenters showcased evidence that brain recordings (fMRI, MEG, ECoG) acquired while participants read or listened to unconstrained speech can be predicted by representations extracted from state-of-the-art text- and speech-based LLMs. In particular, text-based LLMs tend to align better with higher-level language regions, capturing more semantic aspects, while speech-based LLMs excel at explaining early auditory cortical responses. However, purely low-level features can drive part of these alignments, complicating interpretations. New methods, including perturbation analyses, highlight which linguistic variables matter for each cortical area and time scale. Further, “brain tuning” of LLMs—fine-tuning on measured neural signals—can improve semantic representations and downstream language tasks. Despite open questions about interpretability and exact neural mechanisms, these results demonstrate that LLMs provide a promising framework for probing the computations underlying human language comprehension and production at multiple spatiotemporal scales.

Recent high-profile scientific achievements by machine learning (ML) and especially deep learning (DL) systems have reinvigorated interest in ML for automated scientific discovery (eg, Wang et al. 2023). Much of this work is motivated by the thought that DL methods might facilitate the efficient discovery of phenomena, hypotheses, or even models or theories more efficiently than traditional, theory-driven approaches to discovery. This talk considers some of the more specific obstacles to automated, DL-driven discovery in frontier science, focusing on gravitational-wave astrophysics (GWA) as a representative case study. In the first part of the talk, we argue that despite these efforts, prospects for DL-driven discovery in GWA remain uncertain. In the second part, we advocate a shift in focus towards the ways DL can be used to augment or enhance existing discovery methods, and the epistemic virtues and vices associated with these uses. We argue that the primary epistemic virtue of many such uses is to decrease opportunity costs associated with investigating puzzling or anomalous signals, and that the right framework for evaluating these uses comes from philosophical work on pursuitworthiness.

Generative AI is fundamentally transforming the software development industry by improving processes such as software testing, bug detection, bug fixes, and developer productivity. This talk explores how AI-driven techniques, particularly large language models (LLMs), are being utilized to generate realistic test scenarios, automate bug detection and repair, and streamline development workflows. As these technologies evolve, they promise to improve software quality and efficiency significantly. The discussion will cover key methodologies, challenges, and the future impact of generative AI on the software development lifecycle, offering a comprehensive overview of its revolutionary potential in the industry.

Modern artificial intelligence (AI) systems are powered by foundation models. This paper presents a new set of foundation models, called Llama 3. It is a herd of language models that natively support multilinguality, coding, reasoning, and tool usage. Our largest model is a dense Transformer with 405B parameters and a context window of up to 128K tokens. This paper presents an extensive empirical evaluation of Llama 3. We find that Llama 3 delivers comparable quality to leading language models such as GPT-4 on a plethora of tasks. We publicly release Llama 3, including pre-trained and post-trained versions of the 405B parameter language model and our Llama Guard 3 model for input and output safety. The paper also presents the results of experiments in which we integrate image, video, and speech capabilities into Llama 3 via a compositional approach. We observe this approach performs competitively with the state-of-the-art on image, video, and speech recognition tasks. The resulting models are not yet being broadly released as they are still under development.

Nearest-neighbor indexes usually rely on a single distance function, but accurate comparisons can be expensive. This talk proposes a bi-metric framework: a cheap proxy metric builds the index, while the query procedure uses a limited number of evaluations of both the proxy and an expensive ground-truth metric. The theory applies to DiskANN and Cover Tree. When the proxy approximates the ground-truth metric within a bounded factor, the resulting structure can achieve arbitrarily good approximation guarantees under the accurate metric. Experiments on text retrieval using models with very different computational costs show improved accuracy-efficiency tradeoffs on almost all MTEB datasets compared with alternatives such as reranking. Joint work with Haike Xu and Sandeep Silwal.

Dr. Nicholas Blauch will present on his work "Topoformer: Brain-like topographic organization in transformer language models through spatial querying and reweighting". Dr. Blauch is a postdoctoral fellow in the Harvard Vision Lab advised by Talia Konkle and George Alvarez. Paper link: https://openreview.net/pdf?id=3pLMzgoZSA Trends in NeuroAI is a reading group hosted by the MedARC Neuroimaging & AI lab (https://medarc.ai/fmri | https://groups.google.com/g/medarc-fmri).