Topic: anxiety-like behavior

Aims: Psychiatric morbidity and functional limitations are widespread in patients with thermal skin injury. Hyperbaric oxygen therapy (HBO) and antioxidant supplementation have been adjunctive therapy to promote wound healing. We evaluated the effects of HBO (100% O2 at 2.5 ATA for 60 minutes) and the antioxidant supplementation – Filipendula ulmaria (FU) extract (100 mg/kg b.w.), individually, in the treatment of anxiety-like behavior that occurs along the thermal skin injury in rat for seven days. Methods: Anxiety level estimation was performed in the open field and the elevated plus maze te

Dementia, a complex, incurable clinical syndrome marked by progressive cognitive decline, encompasses various types, with Alzheimer's disease (AD) being the most prevalent. The annual increase in AD cases underscores the urgency for innovative antidementia treatments. Mansorin A (MA) and mansonone G (MG) exhibit antioxidant effects on the central nervous system. Given the close association between oxidative stress and AD pathology, MA and MG might alleviate AD-like symptoms. To investigate the anti-dementia potential of MA and MG, the promnesic, anxiolytic, and antioxidant potential of MA and

Anxiety and mood disorders significantly impact individual well-being and societal health, highlighting the need for a thorough understanding of their risk factors. While early life stress is widely recognized as a risk factor for multiple psychiatric conditions, the neurobiological mechanisms driving these effects are yet to be fully understood.In this collaborative study, we investigated the long-lasting consequences of developmental stress on adult brain function, increasing susceptibility to the aforementioned disorders.To investigate the long-lasting consequences of developmental stress,